The TLC blood test is one of the most common blood test ordered by doctors, and TLC stands for ‘Total Leukocyte Count’. Leukocytes are white blood cells which are important components of the blood. The main role of white blood cells or leukocytes is to fight infection and keep the body healthy. Leukocytes are essential for the overall well-being of the body.
The TLC blood test forms a part of the complete blood test which determines other values such as complete blood count (CBC), platelet count, red blood cells count (RBC), and hemoglobin percentage. A DLC test may be ordered along with a TLC test. DLC stands for Differential Leukocyte Count and is done to measure the percentage of each type of white blood cell or leukocyte in the body.
TLC test means the test is done to determine the number of white blood cells in the blood. The WBC count helps determine the body’s capacity to fight diseases.
The normal range for TLC is considered to be between 4000 to 11000 cells/cubic millimeter of blood. A decrease in the TLC count is referred to as leukopenia, and it will cause a decline in the body’s ability to fight diseases. An increase in the TLC count is known as leukocytosis, and it is a condition in which the body produces more WBCs than normal. Leukocytosis is common among people who have an acute infection or illness and in newborn infants.
This test is ordered by the doctor to confirm a diagnosis or to check if the treatment for a particular disease is working well for you.
The WBCs or leukocytes are white colored blood cells that are manufactured in the bone marrow, and move throughout the body in the blood, continuously looking for foreign bodies or invaders such as bacteria and viruses. They are immunity cells that are continually at war with any kind of foreign invaders. When the body is in danger of any illness or infection and a particular body part is involved, the WBCs rush to the affected area to help destroy the invading bodies and protect your body against illnesses.
The WBCs account only for 1% of your blood, but they have a significant effect on the healthiness of your body. There are 5 types of WBCs, each with a different function. Below are the types of WBCs and their functions:
The average lifespan of a leukocyte is 13 to 20 days, and their lifespan in the peripheral blood is only 7 to 10 hours after they migrate from the bone marrow into the bloodstream. This is the reason why a healthy body produces around 100 billion leukocytes per day to replace the perished leukocytes.
As mentioned earlier, a TLC blood test helps doctors confirm a diagnosis and helps them determine the effect of the treatment for a particular disease. This test is often used by doctors to:
A patient is not needed to take any special precautions before undergoing a TLC blood test, but it is important to inform your doctor about any medication you take regularly, and he may ask you to stop taking certain drugs before undergoing the test as some drugs may affect the test results.
A blood sample is obtained from the patient like in any other test, and the TLC is estimated either through a manual/microscopic method or through an automated method that uses an equipment called the hemocytometer.
The TLC normal range for Total Count – WBC is 4,000-11,000 cells/ cumm for all age groups and for Unisex gender. If the test results show any deviation from the TLC normal range is considered to be an indication of a disease.
The normal reference range for adults (males and females) is as follows:
If the results of a TLC blood test show an increase in the number of WBCs, i.e., if the TLC count high when more than 11000 cells/ cubic millimeter of blood, the condition is called Leukocytosis. Leukocytosis may be caused by a number of reasons such as:
If the results of a TLC test show the WBC count to be less than 4000 cells/ cubic millimeter of blood. This condition is referred to as leukopenia, and it may be caused by:
If you are detected with high TLC in blood, there are not many options to help reduce the high TLC. However, aiming to reduce the amount of calorie intake in a day and maintaining a healthy body weight may help reduce the high TLC. Other steps you may take to maintain a normal TLC include:
If your TLC blood test values are lowered, you can work to increase the levels by:
Medically Reviewed By
I am an experienced Medical/Scientific writer with a passion for helping people live a happy healthy life. My thirst for writing has followed me throughout the years – it is there when I wake up, lingering at the edges of my consciousness during the day, and teases me at night as I go to sleep.
Serotonin, commonly referred to as the "feel-good" neurotransmitter, plays a critical role in regulating mood,…
Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) are two neurodevelopmental conditions that, while distinct,…
The year 2024 has seen a significant Listeria outbreak, raising alarms across several countries. Listeria…
Metabolic conditioning (MetCon) has gained significant attention in the fitness world, often hailed as a…
Cooking oils are a staple in every kitchen, playing a crucial role in the flavor,…
Macular amyloidosis is a skin condition characterized by the abnormal deposition of amyloid proteins in…